Managing Patient Health in the Genomic Era

Managing Patient Health in the Genomic Era

Family Health History and Adult Disease Risk

Henrich, Vincent (Professor Emeritus, Former Director of the Center for Biotechnology, Genomics, and Health Research, University of North Carolina, Greensboro, USA); Shirts, Brian H. (Associate Professor, Department of Laboratory Medicine, University of Washington, USA); Orlando, Lori A. (Director, Program in Precision Medicine, Center for Applied Genomics and Precision Medicine, Duke University, USA)

Elsevier Science Publishing Co Inc

12/2019

304

Mole

Inglês

9780128160152

Descrição não disponível.
1. Genomic Medicine Overview Part I. FHH, Genomics, and Disease Risk 2. Family Health History's Place in Genomic Medicine 3. FHH as a driver of genetic testing 4. FHH contextualizes genetic test results 5. FHH help to identify existing and new genetic markers 6. Lineage specific variants: principles and detection (Brian Shirts) 7. FHH, gene-environment interactions 8. Finding Effective Interventions in the Genomic era 9. Tools for FHH collection and Analysis 10. Applying algorithms, Epidemiology, Evidence-based intervention (Beth Hauser) 11. Genetic counseling: description and purpose (Adam Buchanan) 12. Closing the loop: patient followup Part III. Primary Care in the Genomic Era 13. Prognosis for FHH-social networking for extended families, consent issues 14. Conclusion: The future: whole genome sequencing, familial variant database, gene editing
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